Elucidation: It is a three-dimensional spatial region is a spatial region that is of three dimensions. Example of usage: a sphere-shaped region of space; a cube-shaped region of space. Source: Basic Formal Ontology 2.0 SPECIFICATION AND USER’S GUIDE. Corresponding author: Barry Smith. June 26, 2015, https://raw.githubusercontent.com/BFO-ontology/BFO/master/docs/bfo2-reference/BFO2-Reference.pdf. https://www.ebi.ac.uk/ols4/ontologies/bfo/classes/http%253A%252F%252Fpurl.obolibrary.org%252Fobo%252FBFO_0000028